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CRA Response to USC Study on Fructose Ratio in Beverages

Corn Refiners Association Response to USC Study in the Journal Nutrition Claiming a Higher Ratio of Fructose to Glucose in Popular Beverages

June 4, 2014

CONTACT: David Knowles
(202) 534-3494

WASHINGTON, DC – Dr. Michael Goran has used improper methodology to arrive at demonstrably false conclusions about the amount of fructose in certain sweetened beverages. Again. Of the three methodologies employed in his study, none is a valid methodology for measuring sugars in beverages.

In contrast, a new study in the International Journal of Obesity that used validated methodologies for measuring sugars in beverages shows unequivocally (once again) that fructose as a percentage of total sugars in carbonated beverages sweetened with high fructose corn syrup corresponds within acceptable industry tolerances for the 55% minimum stipulated by regulatory standards.

The inappropriate methodologies used in the Goran study are:

  • HPLC, the same methodology used in his demonstrably unsound 2010 study, which was resoundingly discredited in the wake of its release;
  • Metabolomics, a method that has not been validated for measurement of sugars in beverages; and
  • The gas chromatography method that was used is validated for cereals, and not appropriate for analysis of beverages.

To suggest such a widespread, severe, and sustained breakdown of quality control within the beverage industry based on unvalidated testing methods is scientifically and professionally irresponsible.

The assertion made by the authors that fructose has been implicated in multiple metabolic diseases is simply not an accurate reading of the modern scientific literature. Credible scientific research shows that fructose when substituted calorie for calorie with other carbohydrates has no different effects on any metabolic parameter including obesity.

Furthermore, Dr. Goran and the co-authors selectively quote studies which have used enormous amounts of pure fructose and pure glucose, neither of which is normally consumed in this way in the human diet. Their literature review is largely irrelevant to human nutrition.


The Corn Refiners Association (CRA) is the national trade association representing the corn refining industry of the United States. CRA and its predecessors have served this important segment of American agribusiness since 1913. Corn refiners manufacture sweeteners, ethanol, starch, bioproducts, corn oil and feed products from corn components such as starch, oil, protein and fiber.

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